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Unlike immune senescence induced by the passage of time, tumour cells increase the glycolytic flux to resist the adverse effects of this senescence, and the large amounts of lactate produced promotes their own invasive and migratory abilities

Covalent modification of CDK2 by 4-hydroxynonenal as a mechanism of inhibition of cell cycle progression

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5-Amino-1MQ is studied as a selective NNMT inhibitor, allowing researchers to examine what happens when this specific methylation pathway is disrupted