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Mutational analysis of conserved cysteine residues in the Fe/S domain of XPD indicated that an intact Fe/S domain is essential for helicase activity and/or stabilizing the protein structure (Liu et al., 2008

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Apurinic/Apyrimidinic Endonuclease Apurinic/apyrimidinic endonuclease (APE1) is also known as redox effector factor 1 (RF1), human AP endonuclease 1 (HAP1), or apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1