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Tse A, Lee AK, Tse FW

WCleveland2006Onset and progression in inherited ALS determined by motor neurons and microglia.Science31213891392 10

Further, the presence of astrocytic cytoplasmic inclusions, protein aggregates like alpha-synuclein (SNCA), A, and Tau in neurons, can also contribute to neuropathology (Li and Haney, 2020) and appears to be one of the critical features in many neurodegenerative diseases

It is recognized by the Ministry of Food and Drug Safety

However, it has also been shown that claudin-1 overexpression decreased the level of claudin-5 and induced a proinflammatory phenotype in ECs in chronic stroke (Sladojevic et al., 2019)