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Severe kidney impairment and food intake can influence the pharmacokinetic parameters of ALA [54, 55]

sinensis has generated significant breakthroughs in recent years

Desensitization: receptor becomes less responsive when exposed to a high concentration of an agonist drug for a long duration (several minutes)

As the field uncovers the relationship between the symptoms of this condition and neuroinflammation, attention must be paid to the biological mechanisms of neuroinflammation and issues with its potential measurement

Moreover, mechanistic studies offer promising pathways, such as neurotrophin signaling, oxidative stress modulation, and inflammatory regulation, but are still primarily grounded in animal models