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Response: While we monitor the structure of the OPPS and the various APCs, we note that some of the principles guiding the CY 2016 OPPS APC restructuring and consolidation included improved resource and clinical homogeneity, as well as reduced resource overlap in APCs within a clinical family (80 FR 70379)

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Given the autologous origin, its low cost and low risk features of PRP, its a promising choice for osteoarthritis patients to control the symptoms caused by synovitis. A 29-year old male basketball player treated with PRP

A bio-measure alone typically is indicative of some exposure, whereas the biomarker quantifies that exposure, albeit typically with some margin of error in that estimate (Turner and Snyder 2021)