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This study was designed to test whether AOD9604 could damage DNA or cause genetic mutationsimportant safety questions for any compound being considered for human use

Their work found and described several selective NNMT inhibitors, including 5-amino-1-methylquinolinium derivatives

5-amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that methylates nicotinamide using S-adenosylmethionine (SAM)