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But in CNS, where biology depends so heavily on human-specific structure and function, the translation gap remains a serious issue

37 Wulffel, M.G., et al., Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: a randomized, placebo-controlled trial

Then as a graduate student in 1958, John Gurdon discovered in his research work at Oxford that mature cells retain all the information needed to make any cell type of the body encoded somewhere deep within their own DNA [103]