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Nacalai Tesque, Kyoto, Japan) dissolved in PBS every day from 5 to 8 or 12 W (EAAC1 KO mice), or from 3 to 5 W (GLAST KO mice)

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Firstly, in vitro models lack the complexity of the human tumor microenvironment and may not fully recapitulate human cancer biology, limiting the predictive value of preclinical outcomes