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HCG itself is not established as an effective obesity treatment, and very low-calorie diets may come with side effects and risks

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In summary, current therapeutic strategies for PD increasingly focus on modulating microglial function through diverse mechanisms, including polarization shift, ferroptosis inhibition, nano-enabled targeting, and kinase modulation

The downregulation of CBS expression resulted in the decrease of antioxidant proteins NRF2, MnSOD, TRX-2, and GPX4, and the increase of GR and Catalase, signifying a disturbance in the equilibrium between cellular oxidative and antioxidative systems, thereby inducing oxidative stress (Fig