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Thus, the intestine-on-chip was able to recapitulate characteristic EED signatures, like upregulation of antimicrobial genes and downregulation of metallothioneins and genes involved in digestion and metabolism, providing a reliable tool for the disease study and drug testing, as well for developing a personalized therapy

Although menthol and nicotine are known for their individual effects on respiratory health, their combined impact on pulmonary surfactants remains poorly understood

(Vienna) 106 , 317328 (1999)

Mitragynine has 9 times lower binding affinity to mu receptors (MOR) compared to 7-HMG, mitragynine is an MOR antagonist while 7-HMG is a partial agonist (15)

Journal of Medicinal Food, 7(1), 67-78