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doi: 10.1016/j.ecl.2008.08.006 119 HuR

Front Cell Neurosci 14:600758

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A randomized controlled trial on the effect of metformin in CHD patients without diabetes showed that it (2000 mg/day, P.O for 12 months) not only decreased oxidative stress but also lowered left ventricular mass (LVM) and improved blood pressure [227]