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It reverses fatty liver. Treated obese mice showed less severe liver pathology in one research programme

DORA: 48-week weight and metabolic changes in black women with HIV, in a phase IIIb switch study from dolutegravir- or efavirenz- to doravirine-based first-line antiretroviral therapy

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Published research on these studies documented outcomes from approximately 900 adult participants, predominantly individuals classified as clinically obese, though one trial included healthy non-obese volunteers

The peptide works by selectively activating lipolysis (fat breakdown) in adipose tissue while inhibiting lipogenesis (fat storage)