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Given the epidemiology linking each of these independently to increased AD risk, targeting senescent cells in early disease stages (preclinical and/or prodromal) may hold promise to prevent chronic neurodegeneration and dementia

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Furthermore, it has been demonstrated that four distinct generations of d-PLL can be obtained via the slow hydrolysis of the side chain-protected building block Lys (Tfa)-NCA [27]

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Preclinical identification of Sulfasalazine&Rsquo;S therapeutic potential for suppressing colorectal cancer stemness and metastasis through targeting Kras/Mmp7/Cd44 signaling