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Remarkably, Munc18-1 Q301R still stimulated lipid-mixing while Munc18-1 Q301D retained its inhibitory function relative to Munc18-1 wt (Fig

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The concordance between the two assays was high for nine of ten tested CpGs, with Pearson correlations of 0.75 to 0.93, whereas one CpG showed little biological variation within the cohort and a low correlation coefficient (Supplementary Fig

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