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doi: 10.1016/j.nefro.2020.03.005 103 WangJLiuYWangYSunL

Glutathione peroxidase The glutathione peroxidase family comprises multiple isozymes (GPX1-8) existing in distinct subcellular locations and tissues

Oxidative stress and free radical damage are thought to be the main causes of RPE cell damage and AMD progression, and advanced AMD is also related to iron overload in RPE/Bruch membrane (41)