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Likewise, microRNAs can mediate the effects of environmental factors on gene expression and contribute to mechanisms of neuroplasticity and immunological regulation

Q.Z: Investigation, validation, visualization, writingreview and editing

When human SGECs are cultured with IL-6 for 24 to 72 hours, a downregulation of epithelial markers, an upregulation of mesenchymal markers, and a clear morphological change to a mesenchymal phenotype can be observed (56)