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For the in vitro investigation, we established a hepatic inflammatory injury model by stimulating ImKCs with LPS, followed by treatment with DCHD-DS, the TLR4 inhibitor TAK-242, or the NLRP3 inhibitor MCC950

VzquezMeza et al

For example, elevated TMAO is linked to heart disease, but seafood is the biggest source of dietary TMAO and virtually every blue zone (regions where people routinely live to be 100) eats a good amount of fish