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"Sentiment toward these guys is as negative as it's ever been," Emily Field, head of European pharmaceuticals research at Barclays, told CNBC over the phone Wednesday

The SURMOUNT-1 trial demonstrated 20.9% mean body weight reduction with tirzepatide 15mg weekly at 72 weeks, while preclinical 5-amino-1MQ studies showed visceral fat reduction independent of caloric restriction

The approval is a long time coming for ImmunityBio after the FDA rejected Anktivas Biologics License Application in May 2023 due to issues with a pre-license inspection of a third-party manufacturer