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The presence of BRCA1/2 mutations is closely associated with patient responses to platinum-based chemotherapy, with mutated patients typically showing good initial treatment responses that gradually develop resistance over time (89)

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Fatty acids are constituents of phospholipids needed to create cell membranes and nucleotides 29,30

Yang, P., Li, Z., Fu, R., Wu, H

Inverse relationship between age at onset of Huntington disease and paternal age suggests involvement of genetic imprinting