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Flentjar et al., 2002) and larger lesion sizes (Klivenyi et al., 2000) when neurotoxic treatments are injected into brains

Nonetheless, chronic hyperglycemia is the main underlying cause of DPN, which leads to damage at the vascular level and the free passage of glucose to neurons and Schwann cells, resulting in an imbalance between nerve damage and nerve fiber repair (32)

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