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In hypertensive postmenopausal women, a group characterized by high prevalence of endothelial dysfunction and accelerated declines in muscle mass, 4 weeks of CIT supplementation significantly improved superficial femoral artery flow-mediated dilation, and these vascular benefits were amplified when CIT was combined with slow-velocity, low-intensity resistance training

Xu, B., Wu, X., Gong, Y

B12, oral therapy could not only save resources and time, but may also be preferable for patients with coagulation issues (coagulopathies or on blood-thinning medications) and those who are adverse to injections, for example, elderly patients with sarcopenia for whom i.m