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But theres pretty much zero human research to support these claims

After consideration of public comments, we are finalizing this policy as proposed at 427.600 and 428.500

Direct disc research, while limited, is emerging

Maintenance and Prevention:For maintenance therapy or preventive purposes, lower dosages (e.g., 1000 mcg) may be administered less frequently, such as once a month

Further, as we describe elsewhere in this final rule, we anticipate this policy to adjust Shared Savings Program calculations to mitigate the impact of SAHS billing activity would be invoked in rare and extreme cases when CMS identifies a code that meets the high bar to be defined as SAHS billing activity