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IDH1 mutations cause significant metabolic changes, suggesting that tumor cells rely on specific metabolic pathways to complete cell biological processes

For that reason, nootropic peptides should not be treated like casual brain supplements

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GLUT4 trafficking to an insulin-responsive compartment Before insulin stimulation, GLUT4 is sorted away from other secretory cargo in the Golgi and packaged into small, insulin-responsive GSVs that contain a defined proteome (Figure 3) [47]

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