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Laboratory rats were acclimated for 5 days and randomly assigned to their respective treatment group

Inhibition of lipogenesis AOD-9604 not only breaks down existing fat, but also brakes the formation of new fat

To examine the incorporation of GSH-derived cysteine into downstream pathways, we used an inverse stable-isotope labelling approach 34,35

Overall, authors suggest that oxidative stress along with purinoreceptor subtype 7/inflammasome pathway would play a persistent role in oxaliplatin-induced neurotoxicity and its transition from acute to chronic NP