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This paper aims to provide an overview of the current knowledge on the effects of alcohol consumption on epigenetics, with special focus on summarizing the data on the epigenetic regulatory mechanisms involved in the effects of alcohol consumption on the immune microenvironment

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Objective : To investigate the regulatory mechanism of pleckstrin homology-like domain, family A, member 1 (PHLDA1) in sepsis-induced acute lung injury (ALI)

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Funding This work was supported by the Natural Science Foundation of Hebei Province (C2022205026), the Foundation of Hebei Normal University (L2023T05), and the National Natural Science Foundation of China (31472050)

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