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Conibear, A

A phase 3, randomized, open-label study evaluating the safety and efficacy of magrolimab in combination with azacitidine in previously untreated patients with TP53-mutant acute myeloid leukemia

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In the first step, glutamate and cysteine are ligated by -glutamylcysteine synthetase (also known as glutamatecysteine ligase, GCL) to form -glutamylcysteine, utilizing one molecule of ATP