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He and Koniver theorize this could indicate regeneration of pinealocyte function, though no published research has demonstrated this for pinealon specifically

Hopkinson RJ, Barlow PS, Schofield CJ, Claridge TD

While 75% or more of newborns with SCD in sub-Saharan Africa do not make their fifth birthday (McGann, 2014), in medium- to well-resourced countries almost all of affected babies can now expect to live to adulthood but overall survival still lags behind that of a non-SCD person by 2030 years (Telfer et al., 2007