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Senescence defines a distinct subset of myofibroblasts that orchestrates immunosuppression in pancreatic cancer

FIGURE 1 Concerning dimerization, the GSTU dimer has an open V-shaped configuration with 2200 2 of the accessible surface that is buried at the interface, comparable with that of GSTOs (2000 2 ), but smaller than that of GSTFs (2700 2 ) and most other classes of GSTs (28003400 2 ) (Axarli et al., 2010)