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SKU: 84997377484
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Availability: InStock
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According to Sev transcriptional sequencing, the expression of ferroptosis- and mitophagy-related gene-activating transcription factor 4 (ATF4) was enhanced, and Sev induced ferroptosis in glioma cells by activating the ATF4-CHAC1 pathway (Xu et al., 2022)

Most of this iron is located in erythrocytes as hemoglobin (6070%) with the balance located in skeletal muscle, liver, spleen, and bone marrow as storage iron in ferritin and hemosiderin, iron-containing enzymes, and bound to transferrin