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Clinical trials involving over 900 participants confirmed that AOD-9604 has no effect on glucose metabolism, insulin sensitivity, or IGF-1 levels

H.LuoL.XuL.et al (2019)

Why does California want to restrict it

Curcumin formulations with enhanced bioavailability are thought to achieve therapeutic concentrations in plasma, which can reach dermal tissues to exert antiaging effects, particularly relevant for women experiencing estrogen decline [64]