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Co-Expression of Dominant-Negative TGF- Receptor 2 Enhances the Therapeutic Efficacy of Novel TREM1/DAP12-BB-Based CAR-T Cells in Solid Tumours

Analysis of bulk methylation patterns between tumor types indicated that the STING promoter region was hypomethylated in meningioma (average = 0.10, n = 1412 patients) but mostly hypermethylated in glioblastoma (average = 0.72, n = 170 patients) (Fig