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Specifically, ferrous iron, when reacting with hydrogen peroxide, yields the highly reactive hydroxyl radical via the Fenton reaction [198]

Omega-3 PUFAs have a role in immunomodulation by decreasing pro-inflammatory eicosanoids

Cytotoxic CD8(+) T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons

By blending two or more matrix materials and carefully adjusting the ratio of different polymer materials, the complementary advantages of harsh and brittle materials can be harnessed to improve the mechanical strength of MNs [79]

For GSH assay, cells were treated in Earles balanced salt solution (EBSS), supplemented with 25 mM glucose, 4 mM glutamine, 1 X MEM vitamin solution (Life technologies, CA, USA), 0.22% wt/vol NaHCO 3 , 1 mM sodium pyruvate, 0.2% BSA, 25 mM HEPES, 100 U/ml penicillin and 100 g/ml streptomycin in the presence or absence of 1 X MEM amino acid solution (Gibco, CA, USA) with or without 100 M cystine