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[] Other E3 ligases, including ariadne-1 homolog (ARIH1) and seven in absentia homolog 1 (SIAH1), can also mediate mitophagy, indicating functional redundancy

The prevalence of Vitamin B12 deficiency in the elderly population can be as high as 40% in some studies. This shows we need to watch out for Vitamin B12 deficiency in older adults, even more so if they show signs of thrombocytopenia