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Cys and Hcy

From crafting to creating music

(1998) Lancet 351:645-646

The human gene for the heavy subunit has been localized to chromosome 6p12 [10] and the gene for the light subunit to chromosome 1p21 [11]

Bao et al (60) found downregulation of the ferroptosis regulator GPX4 in both Fpnfl/fl/NEXcre (NEX-Cre mice were mated with Fpn-floxed (Fpnfl/fl) mice to generate conditional Fpnfl/fl/NEXcre mice.) and APPswe/PS1dE9 (Carrying genetically modified mice with AD-related mutations: a chimeric mouse/human APP with the Swedish mutation and human PSEN1 lacking exon 9) mouse models compared with controls