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Price: 29.87 USD
Availability: InStock
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Song X, Long D

HIF-1 is further upregulated by GBMs poor perfusion, as its atypical neovascularization contributes to a cycle that exacerbates its hypoxic environment and shields it from current therapies (156, 157, 163)

A pivotal study using a STZ-induced diabetic rat model demonstrated that diabetes markedly reduces NRN1 expression in dorsal root ganglia and sciatic nerve, which are key anatomical structures affected in peripheral neuropathy (Karamoysoyli et al., 2008)