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The RUG group demonstrated pronounced increases in omental fat weight compared with CON, with particularly marked elevation in mesenteric fat weight and marbling score compared to RPG group

They form immune complexes with joint tissue antigens, activate stromal cells, resident macrophages, mast cells, and osteoclasts, release vasoactive mediators and chemokines, recruit leukocytes, and exacerbate inflammation (Malmstrm et al., 2016