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Furthermore, the fact that tracer retention in cortical regions increased with clinical disease severity, as estimated by the Revised ALS Functioning Rating Scale (ALSFRS-R), suggested that OS may be an important factor associated with the development of neurodegeneration in ALS patients [107]

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Furthermore, the addition of a combination of AOXs (ALC, NAC and -lipoic acid) to the cryoprotectant medium of mice embryos resulted in increased blastocyst cryo-survival and viability post-vitrification (216)