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Aug 11 2024 Van Tin et al., Cells, doi:10.3390/cells13161331 Spike Protein of SARS-CoV-2 Activates Cardiac Fibrogenesis through NLRP3 Inflammasomes and NF-B Signaling In vitro study showing that the SARS-CoV-2 spike protein can activate cardiac fibroblasts through ACE2-dependent mechanisms, leading to cardiac fibrosis via the NLRP3 inflammasome and NF-B signaling pathways

EBioMedicine (2018) 30:30316

Our data highlight that GPX3 is expressed and secreted by mouse and human bronchial epithelial cells already under physiological conditions and increased in mouse and human lung fibrosis

doi: 10.1051/medsci/20072310840

Bacteriostatic water (0.9% benzyl alcohol) is preferred over sterile water because it allows multi-dose use without microbial contamination risk