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B Vitamins are particularly important for energy, stable moods, and healthier skin, hair, and eyes

Tails were solubilized in 300 L solubilization buffer (10X SET, 100 mM NaCl, 100 g/mL Proteinase K (Bio Basic PB0451-250)) at 55 C overnight

Skin glow refers to healthy, radiant, even-toned skin the kind that looks well-rested, hydrated, and healthy

This review integrates mechanistic insights with translational advances, outlining how dysregulation of chaperones, autophagy-mitophagy, the ubiquitinproteasome system, and ER stress pathways drive human diseases, while highlighting emerging therapeutic platforms, from pharmacological chaperones and autophagy modulators to targeted protein degradation technologies, CRISPR screens, spatial biology, and AI-guided drug discovery