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In addition, GSTP1 wild-type genotype in combination with GSTM1 null or GSTT1 null genotype increased probability for infertility (OR: 2.47, 95% CI: 1.464.17: and OR: 2.69, 95% CI: 1.395.32, respectively)

Our in vitro IGF1-binding assays showed that IGF1R WT and 163GS bound to IGF1 with similar affinities, indicating that the L1 hairpin mutations did not affect IGF1 binding (Fig