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Emerging evidence further indicates that ferroptosis significantly contributes to tumor suppression, immune regulation and the maintenance of metabolic homeostasis (4)

Agarwal R, Filippatos G, Pitt B, Anker SD, Rossing P, Joseph A, Kolkhof P, Nowack C, Gebel M, Ruilope LM, et al

Recently, the regulation of the glyoxalase I-II system in plants by exogenous application of chemical treatment was investigated in multiple studies [18, 22, 23], and a close connection between the antioxidant and glyoxalase I-II systems during Cd toxicity [24], salt [22] and heat [23] stress was observed

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The later targets specific proteins, such as receptors, on cancerous cells or in the tumor environment