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Track Your Progress: Note pain levels, mobility, or symptom improvements in a journal

Its a powerful theoretical synergy

Of course, people with a proper vitamin B12 deficiency will see more of a benefit, like improvement with less fatigue, nausea, and irritability

The peptides promote remodeling of poorly healed tissue, reduce chronic inflammation, and can restart stalled healing processes

A retrospective study looking at concomitant use of proton pump inhibitors (PPIs) alongside metformin in 614 people with type 2 diabetes in the US found a significant reduction in B12 levels of 34% in patients taking both medications, compared to controls taking either drug alone (Long et al, 2012)