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[PubMed: 7543116] 52

Unfortunately, flavonoids are far from being specific inhibitors of CD38, showing several off-target effects, and also have poor oral pharmacokinetic profile [1,2, 9-13]

London: National Institute for Health and Care Excellence (NICE)

Adipocyte specific KO of ABHD5 decreased lipolysis, resulting in reduced FA flux to the liver, and protection against HFD induced hepatic steatosis (149), suggesting that suppressing adipocyte lipolysis could be protective against FLD