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Swoboda KJ, Scott CB, Reyna SP, Prior T, Chan G, et al

Nature Reviews Cancer, 3 (5), 330338

Contexto de via/mecanismo A sermorelina ativa o receptor do GHRH, iniciando a sinalizao acoplada protena Gs que eleva o cAMP intracelular e ativa as vias transcricionais dependentes da protena quinase A

Paracellular intestinal permeability can be assessed in vivo by using different molecules (e.g., sugars, polyethylene glycols, 51 Cr-EDTA) and ex vivo in Ussing chambers combining electrophysiology and probes of different molecular sizes