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This correction is important because of the relatively small volumes of distribution of these water-soluble drugs

122 TranT

Approximately three quarters of these patients have other clear signs and symptoms of central nervous system involvement, occasionally with onset and progression in the teenage years (71

In newborns with BPD, nuclear SIRT1 expression in PBMCs collected by tracheal aspiration is lower and nuclear SIRT1 localization is substantially lower than those in normal neonates (56)