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7,8 Clinical management largely comprises surgical resection, and no effective pharmacological agent is yet available for effective treatment or cure, although some agents have shown promising results in preclinical or clinical trials, and will be discussed in detail in this review

En cas de surdosage il peut survenir une diarrhe lodeur de poisson 5

Hum Reprod Update 18:525535 Morita Y, Perez GI, Paris F, Miranda SR, Ehleiter D, Haimovitz-Friedman A, Fuks Z, Xie Z, Reed JC, Schuchman EH et al (2000) Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy

However, GPX4 proved to be a more attractive candidate for silencing lipooxygenases and influencing cytokine signalling (45)

doi: 10.1186/s13024-021-00427-6 173