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GX: Conceptualization, Writing review and editing

This pooled lentiviral library was generated by the Hahn lab and contains 8258 amino acid variants, spanning the entirety of the TP53 gene [19]

NAC is FDA approved with known pharmacokinetics and pharmacodynamics in human neonates and could rapidly be translated into a Phase 1 clinical trial for the treatment of NAS

Validation of reference gene stability for APAP hepatotoxicity studies in different in vitro systems and identification of novel potential toxicity biomarkers

In addition, TQ and THQ are usually present in the form of glycosidically bound aglycones, which easily cross the blood-brain barrier, hence, possibly related to its neuroprotective effects [19]