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We further demonstrated that carrying Desulfovibrionale was related to an increase of secondary bile acid production due to activated bile acid dehydroxylation of gut microbiota, leading to an increase of bile acid hydrophobicity which facilitated intestinal cholesterol absorption, resulting in hepatic accumulation of cholesterol and enhancement of biliary cholesterol secretion

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Molecular mechanism of doxorubicin-induced cardiomyopathy: An update