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focused on activating transcription factor 3 ( ATF3 ), a gene whose role in tumor initiation and progression remains controversial [209]

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You can also view the NCDHHS Respiratory Illness Communications Toolkit, available in English and Spanish.

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CpG methylation induces histone deacetylation, chromatin remodeling, and gene silencing through a transcription repressive complex, which includes SMRT (silencing mediators of retinoic acid and thyroid receptor), mSin3a, RbAp46/48, and the formation around mSin3a The two histone deacetylases HDAC1 and HDAC2

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Ellis RE, Yuan J, Horvitz HR: Mechanisms and functions of cell death

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