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Senescence is usually triggered by various stress signals, which elicit abnormal cells

Metabolomic studies have further revealed that serum levels of sphingomyelin (SM) and its hydroxylated form (SM [OH]) are significantly reduced in COPD patients, with SM C24:1 levels exhibiting a negative correlation with glucose clearance

This synthetic peptide acts primarily through modulation of cellular pathways and enzymatic activities, enhancing growth factor sensitivity, influencing gene expression, and supporting mitochondrial ATP production